KCNA1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65292-50, BS65292-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Swiss-Prot: Q09470

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

All Applications: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Background: potassium voltage-gated channel subfamily A member 1(KCNA1) Homo sapiens This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq, Jul 2008]

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: KV1.1 Polyclonal Antibody detects endogenous levels of KV1.1 protein.

Bioworld Molecular Weight: ~ 57 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of HeLa cells using KV1.1 Polyclonal Antibody diluted at 1：2000, Western blot analysis of lysates from HUVEC, MCF-7, and HeLa cells, using KCNA1 Antibody. The Lane on the right is blocked with the synthesized peptide., Western blot analysis of the lysates from HepG2 cells using KCNA1 antibody.

Alternative Name: KCNA1; Potassium voltage-gated channel subfamily A member 1; Voltage-gated K(+) channel HuKI; Voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1

Immunogen: The antiserum was produced against synthesized peptide derived from human KCNA1. AA range:256-305

Conjugate: Unconjugated

Modification: Unmodified