BRI3 Polyclonal Antibody

Catalogue Numbers: BS60121-50, BS60121-100

Sizes: 50µl, 100µl

Alternative Name: Brain protein I3; pRGR2; BRI3

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O95415

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: BRI3 (brain protein I3), also known as pRGR2 or I3, is a 125 amino acid multi-pass membrane protein. The gene that encodes BRI3 maps to human chromosome 7, which is about 158 milllion bases long, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: BRI3 polyclonal antibody detects endogenous levels of BRI3 protein.

Bioworld Molecular Weight: ~ 14 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of BRI3 polyclonal antibody at 1:500 dilution
Lane 1: Hela whole cell lysate
Lane 2: Mouse brain tissue lysate
Lane 3: Rat colon tissue lysate

Immunogen: A synthetic peptide corresponding to residues in Human BRI3.

Conjugate: Unconjugated

Modification: Unmodified