LPHN1 Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS65810-50, BS65810-100 Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Swiss-Prot: O94910 Host: Rabbit Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Applications: IHC-P All Applications: IHC-P=1:100-500 Background: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008] Purification and Purity: affinity purified by Protein A Storage and Stability: Store at 4°C short term. Aliquot and store at -17°C long term. Avoid freeze-thaw cycles. Specificity: LPHN1 Polyclonal Antibody detects endogenous levels of LPHN1 protein. Bioworld Molecular Weight: ~160 kDa Note: For research use only, not for use in diagnostic procedure. Extra Notes: Paraformaldehyde-fixed, paraffin embedded (rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes;Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (LPHN1) Polyclonal Antibody, Unconjugated at 1:200 overnight at 4°C Alternative Name: Calcium independent alpha latrotoxin receptor 1; Calcium-independent alpha-latrotoxin receptor 1; CIRL-1; CIRL1; CL1; CLIBA; G protein-coupled receptor for alpha-Latrotoxin; KIAA0821; Latrophilin 1; Latrophilin-1; Latrophilin1; LEC2; Lectomedin 2; Lectomedin-2; LPHN 1; LPHN1; LPHN1_HUMAN. Immunogen: KLH conjugated synthetic peptide derived from human LPHN1:201-300/1474 Conjugate: Unconjugated Modification: Unmodified