Recombinant Human LMIR2/CD300C Protein (His Tag)

Size: 50μg

Catalogue Numbers: PKSH032701-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: LMIR2; CD300C

Target Synonym: CMRF35-Like Molecule 6; CLM-6; CD300 Antigen-Like Family Member C; CMRF35-A1; CMRF-35; Immunoglobulin Superfamily Member 16; IgSF16; CD300c; CD300C; CMRF35; CMRF35A; CMRF35A1; IGSF16

UNIProt ID: Q08708

Research Areas: immunology

Target Species: Human

Expression Host: HEK293 Cells

Fusion Tag: C-6His

Accession: Q08708

Background: CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells; granulocytes; most myeloid cells; dendritic cells; and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.

Sequence: Gly21-Arg183

Purity: > 90 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 18.9 kDa

Observed MW: 40 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only