GALK1 Polyclonal Antibody

Catalogue Numbers: BS5729-50, BS5729-100

Sizes: 50µl, 100µl

Alternative Name: Galactokinase; Galactose kinase; GALK1; GALK

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P51570

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHCICC

All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200
ICC: 1:50~1:200

Background: Galactose kinase (GALK1), also often designated galactokinase, is important in the first step of the galactose metabolism pathway. GALK1, which belongs to the GHMP kinase family of proteins, is a crucial enzyme for galactose metabolism. Defects in the gene encoding for galactose kinase, GALK1, can cause galactosemia II, an autosomal recessive disorder characterized by congenital cataracts during infancy, often within the first two weeks of life. In the adult population it can cause presenile cataracts that are secondary to accumulation of galactitol in the lens of the eye.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: GALK1 polyclonal antibody detects endogenous levels of GALK1 protein.

Bioworld Molecular Weight: ~ 42 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of GALK1 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T cell lysate
Lane 2: sp2/0 cell lysate
Lane 3: Rat liver tissue lysate

Immunogen: Synthetic peptide, corresponding to amino acids 4-49 of Human GALK1.

Conjugate: Unconjugated

Modification: Unmodified