Dsg2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5028-50, ES5028-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016],

Alternate Name: DSG2; CDHF5; Desmoglein-2; Cadherin family member 5; HDGC

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human DSG2. AA range:401-450

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 140kD

Human Gene ID: 1829

Human SWISS Prot NO: Q14126

Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.

Research Use Only