SOCS-1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA20625-50, RA20625-100

Citations, Manuals and MSDS Available upon request.

Background: suppressor of cytokine signaling 1 (SOCS1) Homo sapiens This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN) -gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IF: 1:50-200 WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300

Alternative Names: SOCS1; SSI1; TIP3; Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3

Applications: IF/ICC; WB; IHC-p; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 8651

Protein MW (KDa): 38

SWISS: O15524

Source: Rabbit

Research Use Only