(E/Z)-SIB-1893 is a racemic compound of (E)-SIB-1893 and (Z)-SIB-1893 isomers. (E)-SIB-1893 is a selective non-competitive metabotropic glutamate subtype 5 receptor (mGluR5) antagonist.

Product information

CAS Number: 6266-99-5

Molecular Weight: 195.26

Formula: C14H13N

Chemical Name: 2-methyl-6-[(Z)-2-phenylethenyl]pyridine

Smiles: CC1=CC=CC(/C=C\C2C=CC=CC=2)=N1

InChiKey: SISOFUCTXZKSOQ-KHPPLWFESA-N

InChi: InChI=1S/C14H13N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-11H,1H3/b11-10-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

(E)-SIB-1893 produces hypothermia in freely moving rats in a dose-dependent manner.

Products are for research use only. Not for human use.