Myosin Phosphatase Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16368-50, BZ16368-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: O14974

Host: Rabbit

Reactivity: Human, Mouse, Rat, Monkey

Applications: WB, IHC-P, ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background: Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 115 kDa; Observed MW: 140 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Myosin Phosphatase in various lysates using Myosin Phosphatase antibody., Western blot analysis of Myosin Phosphatase in 293T lysates using MYPT1 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using MYPT1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right., Western blot analysis of Myosin Phosphatase in COS7 lysates using Myosin Phosphatase antibody. The Lane on the right is blocked with the synthesized peptide.

Alternative Name: PPP1R12A; MBS; MYPT1; Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit

Immunogen: The antiserum was produced against synthesized peptide derived from human MYPT1. AA range:661-710

Conjugate: Unconjugated

Modification: Unmodified