FABP4 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90489-50, BS90489-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P15090(Human) P04117(Mouse) P70623(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, IHC

All Applications: WB:1:500-1:2,000
ICC:1:100-1:500
IHC:1:50-1:200

Background: Fatty acid-binding proteins, designated FABPs, are a family of homologous, cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport, and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epidermis (E-FABP, also designated psoriasis-associated FABP or PA-FABP), muscle and heart (H-FABP, also designated mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP), myelin (M-FABP) and testis (T-FABP). The human A-FABP gene is organized into 4 exons, maps to chromosome 8q21, and encodes a 132-amino acid protein. A-FABP protein comprises approximately 1% of the total cytosolic protein in human adipose tissue.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: FABP4 polyclonal antibody detects endogenous levels of FABP4 protein.

Bioworld Molecular Weight: 15 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of FABP4 on mouse heart cells lysates using anti-FABP4 antibody at 1/500 dilution., ICC staining FABP4 in MCF-7 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: ALBP, A-FABP, AFABP, FABP4, 3T3-L1 lipid-binding protein, 422/aP2, A-FABP, adipocyte, Adipocyte lipid binding protein, Adipocyte lipid-binding protein, Adipocyte protein AP2, Adipocyte-type fatty acid-binding protein, AFABP, ALBP, ALBP/Ap2, aP2, Epididymis secretory protein Li 104, FABP, FABP4, FABP4, Fatty acid binding protein 4 adipocyte, Fatty acid binding protein 4, Fatty acid binding protein adipocyte, Fatty acid-binding protein 4, Fatty acid-binding protein, HEL S 104, Lbpl, Myelin P2 protein homolog, P15, P2 adipocyte protein, Protein 422,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified