Recombinant Human Cystatin C/CST3 Protein (E.coli, His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH032324-10, PKSH032324-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: Cystatin C; CST3

Target Synonym: ARMD11; Gamma-trace; Neuroendocrine basic polypeptide; Post-gamma-globulin; Cystatin-3

UNIProt ID: P01034

Research Areas: Tags & Cell Markers; Cell biology; Cardiovascular; Stem cells

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-6His

Accession: P01034

Background: Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B; H; K; L and S. As an inhibitor of cysteine proteinases; Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently; it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition); such as Alzheimer's disease.

Sequence: Gly26-Ala146

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM HEPES; 150mM NaCl; pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 16.5 kDa

Observed MW: 16 kDa

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Research Use Only