HIF-2α-IN-1 is a HIF-2α inhibitor has an IC50 of less than 500 nM in HIF-2α scintillation proximity assay.IC50 value: ＜ 500 nMTarget: HIF-2α

Product information

CAS Number: 1799948-06-3

Molecular Weight: 405.30

Formula: C16H8F5NO4S

Chemical Name: 3-{[(3R)-4-(difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-dioxo-2,3-dihydro-1λ⁶-benzothiophen-5-yl]oxy}-5-fluorobenzonitrile

Smiles: N#CC1=CC(F)=CC(=C1)OC1=CC=C2C([C@@H](O)C(F)(F)S2(=O)=O)=C1C(F)F

InChiKey: HZDKYXAZAPXCKQ-CQSZACIVSA-N

InChi: InChI=1S/C16H8F5NO4S/c17-8-3-7(6-22)4-9(5-8)26-10-1-2-11-13(12(10)15(18)19)14(23)16(20,21)27(11,24)25/h1-5,14-15,23H/t14-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (246.73 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.