ATPBD3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA22241-50, RA22241-100

Citations, Manuals and MSDS Available upon request.

Background: function:Plays a central role in 2-thiolation of mcm (5) S (2) U at tRNA wobble positions of tRNA (Lys), tRNA (Glu) and tRNA (Gln) . Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.,pathway:tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.,similarity:Belongs to the ttcA family. CTU1/NCS6/ATPBD3 subfamily.,subunit:Component of a complex at least composed of URM1, CTU2/NCS2 and ATPBD3/NCS6. May for a heterodimer with CTU2/NCS2.,

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: CTU1; ATPBD3; NCS6; Cytoplasmic tRNA 2-thiolation protein 1; ATP-binding domain-containing protein 3; Cancer-associated gene protein; Cytoplasmic tRNA adenylyltransferase 1

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 90353

Protein MW (KDa): 36

SWISS: Q7Z7A3

Source: Rabbit

Research Use Only