PHKB Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28734-50, RA28734-100

Citations, Manuals and MSDS Available upon request.

Background: phosphorylase kinase regulatory subunit beta (PHKB) Homo sapiens Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Alternative Names: PHKB; Phosphorylase b kinase regulatory subunit beta; Phosphorylase kinase subunit beta

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 5257

Protein MW (KDa): 124

SWISS: Q93100

Source: Rabbit

Research Use Only