Glymidine sodium is a sulfonamide hypoglycemic agent which stimulates insulin secretion.

Product information

CAS Number: 3459-20-9

Molecular Weight: 331.32

Formula: C13H14N3NaO4S

Chemical Name: Benzenesulfonamide, N-(5-(2-methoxyethoxy)-2-pyrimidinyl)-, sodium salt

Smiles: [Na+].COCCOC1=CN=C([N-]S(=O)(=O)C2C=CC=CC=2)N=C1

InChiKey: NUQDEHHKOXSIEA-UHFFFAOYSA-N

InChi: InChI=1S/C13H14N3O4S.Na/c1-19-7-8-20-11-9-14-13(15-10-11)16-21(17,18)12-5-3-2-4-6-12;/h2-6,9-10H,7-8H2,1H3;/q-1;+1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Hardison WG, Wood CA. Importance of bicarbonate in bile salt independent fraction of bile flow. Am J Physiol. 1978 Aug;235(2):E158-64. PubMed PMID: 150796.
2. Losert W, Loge O, Jahn P. [Comparison of the beta-cytotropic effect of glymidine sodium (glycodiazine), glucagon, and isopropylnoradrenaline in rats]. Arzneimittelforschung. 1973 Sep;23(9):1251-60. German. PubMed PMID: 4149442.
3. Loge O, Losert W, Jahn P. [Influence on serum insulin concentration of sodium glymidine (glykodiazine), isopropylnorepinephrine, glucagon and theophylline in Chinese hamsters with spontaneous or streptozotocin-induced diabetes mellitus]. Res Exp Med (Berl). 1973 Jun 19;160(4):292-306. German. PubMed PMID: 4269691.
4. Losert W, Rosenthal K, Jahn P, Sitt R. [Comparative studies on the effect of sodium glymidine, glucagon and isopropylnoradrenaline on insulin secretion in rats]. Naunyn Schmiedebergs Arch Pharmakol. 1970;266(4):397-8. German. PubMed PMID: 4397505.

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