Stat4 (phospho Tyr693) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21261-50, RA21261-100

Citations, Manuals and MSDS Available upon request.

Background: signal transducer and activator of transcription 4 (STAT4) Homo sapiens The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/5000. Not yet tested in other applications.

Alternative Names: STAT4; Signal transducer and activator of transcription 4

Applications: WB; IHC-p; IF (paraffin section) ; IP; ELISA

Species Cross-Reactivity: Human; Mouse; Rat; Monkey

GeneID (Human): 6775

Protein MW (KDa): 86

SWISS: Q14765

Source: Rabbit

Research Use Only