NF-KB p100 Polyclonal Antibody

Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16886-50, BZ16886-100

Swiss-Prot: Q00653

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, IP

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: Transcription factors of the nuclear factor κ B (NF-κB)/Rel family play a pivotal role in inflammatory and immune responses. NF-κB-activating agents can induce the phosphorylation of IκB proteins, targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Calculated MW: 97 kDa; Observed MW: 120,52 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of NF-KB p100 / p52 in Jurkat lysates; mouse heart lysates using NF-KB p100 antibody.

Alternative Name: NFKB2; LYT10; Nuclear factor NF-kappa-B p100 subunit; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; Oncogene Lyt-10; Lyt10

Immunogen: A synthesized peptide derived from human NFkB p100 / p52

Conjugate: Unconjugated

Modification: Unmodified