Blk (phospho Tyr501) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7144-50, ES7144-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010],

Alternate Name: BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human BLK around the phosphorylation site of Tyr501. AA range:456-505

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 640

Human SWISS Prot NO: P51451

Subcellular Location: Cell membrane; Lipid-anchor. Present and active in lipid rafts. Membrane location is required for the phosphorylation of CD79A and CD79B (By similarity).

Research Use Only