Recombinant Human Cardiotrophin-1/CTF1 Protein (His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSH032175-10, PKSH032175-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: Cardiotrophin-1; CTF1

Target Synonym: Cardiotrophin-1; CT-1; CTF1;

UNIProt ID: Q16619

Research Areas: Cardiovascular; immunology

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-6His

Accession: Q16619

Background: Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, thymus, testis and small intestine. The protein exerts its cellular effects by interacting with the glycoprotein 130 (gp130)/leukemia inhibitory factor receptor beta (LIFR) heterodimer. In addition, CT-1 activates phosphatidylinositol 3-kinase (PI-3 kinase) in cardiac myocytes and enhances transcription factor NF-κB DNA -binding activities.

Sequence: Met 1-Ala201

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 22.6 kDa

Observed MW: 25 kDa

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Research Use Only