UK51656 is a calcium antagonist with IC50 of 4 nM.

Product information

CAS Number: 88150-59-8

Molecular Weight: 465.93

Formula: C22H28ClN3O6

Chemical Name: 3-ethyl 5-methyl 2-({2-[(carbamoylmethyl)amino]ethoxy}methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

Smiles: CC1NC(COCCNCC(N)=O)=C(C(C=1C(=O)OC)C1=CC=CC=C1Cl)C(=O)OCC

InChiKey: FAKQIHAUXYAVJI-UHFFFAOYSA-N

InChi: InChI=1S/C22H28ClN3O6/c1-4-32-22(29)20-16(12-31-10-9-25-11-17(24)27)26-13(2)18(21(28)30-3)19(20)14-7-5-6-8-15(14)23/h5-8,19,25-26H,4,9-12H2,1-3H3,(H2,24,27)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

UK51656 has an elimination half-life of 4.7 h, which is consistent with its duration of action in the anesthetized dog. The effect of UK51656 on coronary vascular resistance, has markedly long durations, being over 5 h.

Products are for research use only. Not for human use.