NUP50 Monoclonal Antibody

Catalogue Numbers: MB67245-50, MB67245-100

Sizes: 50µl, 100µl

Product: Mouse IgG1 kappa. Supplied in crude ascites with 0.01% sodium azide.

Swiss-Prot: Q9UKX7

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Component of the nuclear pore complex that has a direct role in nuclear protein import. Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling. Interacts with regulatory proteins of cell cycle progression including CDKN1B (By similarity). This interaction is required for correct intracellular transport and degradation of CDKN1B (By similarity).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of NUP50 protein.

Extra Notes: Western blot analysis of NUP50 expression in Jurkat (A) whole cell lysates.

Bioworld Molecular Weight: ~ 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: NPAP60L; Nuclear pore complex protein Nup50; 50 kDa nucleoporin; Nuclear pore-associated protein 60 kDa-like; Nucleoporin Nup50

Immunogen: Recombinant fusion protein of human NUP50. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified