Nln activator 1 is a first-in-class peptidomimetic neurolysin activator possessing enhanced brain penetration and stability.

Product information

CAS Number: 2659214-18-1

Molecular Weight: 281.31

Formula: C15H15N5O

Chemical Name: (2S)-2-amino-3-(1H-imidazol-5-yl)-N-(quinolin-8-yl)propanamide

Smiles: N[C@@H](CC1=CN=CN1)C(=O)NC1=CC=CC2=CC=CN=C21

InChiKey: RAPFGLSZEYHZEU-LBPRGKRZSA-N

InChi: InChI=1S/C15H15N5O/c16-12(7-11-8-17-9-19-11)15(21)20-13-5-1-3-10-4-2-6-18-14(10)13/h1-6,8-9,12H,7,16H2,(H,17,19)(H,20,21)/t12-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Rahman MS, et al. Discovery of First-in-Class Peptidomimetic Neurolysin Activators Possessing Enhanced Brain Penetration and Stability. J Med Chem. 2021 Sep 9;64(17):12705-12722.

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