GLUT2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90583-50, BS90583-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P11168(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, IHC FC

All Applications: WB:1:500-1:1,000
FC:1:50-1:100
IHC:1:50-1:200

Background: Glucose is fundamental to the metabolism of mammalian cells. Its passage across cell membranes is mediated by a family of transporters termed glucose transporters or Gluts. Glut1, Glut3 and Glut4 are high-affinity transporters, whereas Glut2 is a low-affinity transporter. In adipose and muscle tissue, insulin stimulates a rapid and dramatic increase in glucose uptake, which is largely due to the redistribution of the insulin-inducible glucose transporter Glut4. In response to insulin, Glut4 is quickly shuttled from an intracellular storage site to the plasma membrane, where it binds glucose. In contrast, the ubiquitously expressed glucose transporter Glut1 is constitutively targeted to the plasma membrane and shows a much less dramatic translocation in response to insulin. Glut2 expression is seen in pancreatic beta cells, hepatocytes and basolateral membranes of intestinal and epithelial cells, while the highest expression of Glut3 has been found in neuronal tissue.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: GLUT2 polyclonal antibody detects endogenous levels of GLUT2 protein.

Bioworld Molecular Weight: 57 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-GLUT2 antibody. Counter stained with hematoxylin., Immunohistochemical analysis of paraffin-embedded human kideny tissue using anti-GLUT2 antibody. Counter stained with hematoxylin.

Alternative Name: GLUT-2, SLC2A2, liver, Glucose Transporter 2, Glucose Transporter GLUT2, Glucose transporter type 2, Glucose transporter type 2 liver, Glucose transporter, liver/islet, GLUT-2, GLUT2, GTR2, GTT2, SLC2A2, Solute carrier family 2 (facilitated glucose transporter) member 2, Solute carrier family 2 facilitated glucose transporter member 2, Solute carrier family 2, facilitated glucose transporter member 2,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified