PDE4B rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES14187-50, ES14187-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Rat

Immunogen: Synthesized peptide derived from human PDE4B AA range: 103-153

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 5142

Human SWISS Prot NO: Q07343

Subcellular Location: [Isoform PDE4B5]: Cytoplasm. Cell membrane.

Research Use Only