Rho A + B + C Rabbit Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS40155-50, BS40155-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P61586/P62745/P08134

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC ICC/IF FC

All Applications: WB 1:500~1:2000 IHC 1:500~1:1000 ICC/IF 1:100~1:500 FC 1:200

Background: RhoA , RhoB , RhoC is a small G protein of the Rho family. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. The three mammalian Rho proteins (A, B and C) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.

Purification and Purity: Affinity-chromatography

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Rho A + B + C Antibody detects endogenous levels of total Rho A + B + C

Bioworld Molecular Weight: 22kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Rho A + B + C expression in (1) Jurkat cell lysate; (2) NIH/3T3 cell lysate., Immunohistochemical analysis of paraffin-embedded human lung carcinoma, using Rho A + B + C Antibody., Immunofluorescent analysis of Hela cells, using Rho A + B + C Antibody.

Alternative Name: ARH12, ARH6; ARH9; ARHA; ARHA2; H12; RHO12; Transforming protein RhoA; RHOA; RHOB; RHOC;

Immunogen: A synthesized peptide derived from human Rho A + B + C

Conjugate: Unconjugated

Modification: Unmodified