P2X3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3941-50, ES3941-100

Citations, Manuals and MSDS Available upon request.

Background: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008],

Alternate Name: P2RX3; P2X purinoceptor 3; P2X3; ATP receptor; Purinergic receptor

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human P2RX3. AA range:81-130

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 44kD

Human Gene ID: 5024

Human SWISS Prot NO: P56373

Subcellular Location: Cell membrane; Multi-pass membrane protein.

Research Use Only