Cleaved-Caspase-7 p20 (D198) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA23469-50, RA23469-100

Citations, Manuals and MSDS Available upon request.

Background: caspase 7 (CASP7) Homo sapiens This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Alternative Names: CASP7; MCH3; Caspase-7; CASP-7; Apoptotic protease Mch-3; CMH-1; ICE-like apoptotic protease 3; ICE-LAP3

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 840

Protein MW (KDa): 20

SWISS: P55210

Source: Rabbit

Research Use Only