Ribosomal Protein L7 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3369-50, ES3369-100

Citations, Manuals and MSDS Available upon request.

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical

Alternate Name: RPL7; 60S ribosomal protein L7

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat; Cat

Immunogen: The antiserum was produced against synthesized peptide derived from human RPL7. AA range:199-248

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 32kD

Human Gene ID: 6129

Human SWISS Prot NO: P18124

Subcellular Location: nucleus, nucleolus, cytoplasm, cytosol, ribosome, focal adhesion, membrane, cytosolic large ribosomal subunit, intracellular ribonucleoprotein complex, extracellular exosome,

Research Use Only