GMFG Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB66726-50, MB66726-100

Product: Mouse IgG1. Supplied in crude ascites with 0.01% sodium azide.

Swiss-Prot: O60234

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB (1/2000 - 1/10000)

Background: GMF-γ (glia maturation factor, γ), also known as GMFG, is a 142 amino acid protein that belongs to the GMF subfamily of the larger Actin-binding protein ADF family. GMF-γ is expressed predominantly in lung, heart and placenta.GMF-γ is considered a candidate regulatory growth factor protein, mediating both paracrine and autocrine cell-cell interactions. GMF-γ is phosphorylated at N-terminal serine, and its phosphorylation is enhanced by coexpression of dominant active Rac 1 and Cdc42. GMF-γ expression is significantly increased in a cardiac ischemia/reperfusion model where inflammation and angiogenesis take place actively. As a regulator of Actin-based cellular functions, GMF-γ may provide a novel approach to modulate the pathophysiology of cardiovascular diseases. GMF-γ is primarily found in proliferative and differentiative organs.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of GMFG protein.

Bioworld Molecular Weight: ~ 14 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of GMFG expression in Jurkat (A) whole cell lysates., ???, ???, ???

Glia maturation factor gamma; GMF-gamma

Immunogen: Recombinant fusion protein of human GMFG. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified