MSH2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES6281-50, ES6281-100

Citations, Manuals and MSDS Available upon request.

Background: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],

Alternate Name: MSH2; DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human MSH2. AA range:541-590

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 100kD

Human Gene ID: 4436

Human SWISS Prot NO: P43246

Subcellular Location: Nucleus. Chromosome.

Research Use Only