NFκB-p65 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA20544-50, RA20544-100

Citations, Manuals and MSDS Available upon request.

Background: RELA proto-oncogene, NF-kB subunit (RELA) Homo sapiens NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: RELA; NFKB3; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

Applications: WB; IHC-p; IF (paraffin section) ; IP; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 5970

Protein MW (KDa): 60

SWISS: Q04206

Source: Rabbit

Research Use Only