RelB Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91165-50, BS91165-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q01201(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, ICC/IF, IHC, IP,

All Applications: WB:1:1,000
ICC:1:50-1:200
IHC:1:50-1:200

Background: The NFκB transcription factor was originally identified as a protein complex consisting of a DNA binding subunit and an associated protein. The DNA binding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino terminus of a precursor designated p105. A second protein designated p52 (previously referred to as p49) has been identified that can act as an alternative NFκB subunit. Rel B does not bind with high affinity to NFkB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to that of p50 NFκB homodimers. However, Rel B/p50 heterodimers, in contrast to NFκB heterodimers, transactivates transcription of promotors containing κB binding sites.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: RelB polyclonal antibody detects endogenous levels of RelB protein.

Bioworld Molecular Weight: 62 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: ICC staining RelB in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., ICC staining RelB in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Alternative Name: RELB, I REL, I-Rel, IREL, Nuclear factor of kappa light polypeptide gene enhancer in B cells 3, relB, RELB, Reticuloendotheliosis viral oncogene homolog B, Transcription factor Rel B, Transcription factor RelB, v rel avian reticuloendotheliosis viral oncogene homolog B, v rel reticuloendotheliosis viral oncogene homolog B,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified